Test Name

Creatinine Serum

Test Code

201

Unit

mg/dL

Specimen

Serum, plasma (urgent for
CT)

Station

Chemistry

Synonym Name/Abbreviation

Creat

CPT Code

82565

Performing Facility

American Medical Labs, Herzliya
Pituah

Analyzer

Roche cobas 6000

Test Method

Kinetic Jaffe’, rate blanked, compensated, traceable to
IDMS

AML Preferred Tube

5 mL SST gel

Storage Instructions

Refrigerated.

Separate serum from cells within 45 minutes;

Stability:

7 days at 15 to 25 ^oC

or at 2 to 8 ^oC

3 months at -15 to -25^oC.

Min. Volume

1 mL

Comments

Causes of high creatinine include renal diseases and
insufficiency with decreased glomerular filtration (uremia or azotemia if
severe); urinary tract obstruction; reduced renal blood flow including
congestive heart failure, shock and dehydration; rhabdomyolysis causes
high serum creatinine, which may be elevated out of proportion to BUN, or
to the reduction in renal function. Causes of low creatinine include small
stature, debilitation, decreased muscle mass, some complex cases of severe
hepatic disease. 

Turn-Around-Time

One day

Intended Use

A renal function test, providing a rough approximation of
glomular filtration.

Limitations

Invalid in hemolytic serum. Increased serum creatinine
results may occur from noncreatinine substances, including meat ingestion,
glucose, pyruvate, uric acid, fructose guanidine, ketonemia
(acetoacetate), hydandoin, ascorbic acid and cephalosporin; Measuring
range: Serum/Plasma = 0.17 to 24.9 mL, Urine = 4.2 to 622
mg/dL.

Patient Preparation

No patient preparation
needed

Reasons for Rejection

Hemolysis; improper
labeling

Adult Reference Ranges

Male: 0.70 to 1.20 mg/dL;

Female: 0.50 to 0.90
mg/dL.