Test
Name

Folic Acid

Test Code

519

Unit

ng/mL

Station

Chemistry

Synonym Name/Abbreviation

Folate

CPT Code

82746

Performing Facility

American Medical Labs, Herzliya
Pituah

Analyzer

Roche cobas 6000

Test Method

Electrochemiluminescence immunoassay
(ECLIA)

AML Preferred Tube

Serum

Storage Instructions

Refrigerated

Stability:

2 hours at  25 ^oC

48 hours at 2 to 8 ^oC

28 days at -20 ^oC

Protect from light.

Min. Volume

1 mL

Comments

Folic acid is strongly influenced by diet and dietary
supplementation

Turn-Around-Time

One day.

Intended Use

Detect folate deficiency; monitor therapy with folate;
evaluate megaloblastic and macrocytic anemia; evaluate alcoholic patients
and those with prior jejunoileal bypass for morbid obesity or those with
intestinal blind-loop syndrome.

Limitations

In patients receiving therapy with high biotin doses (ie,
> 5 mg/day), no sample should be taken until at least eight hours after
the last biotin administration.
In rare cases, interference due to extremely high titers of
antibodies to streptavidin and ruthenium can occur. The test contains
additives that minimize these effects. It is contraindicated to measure
samples of patients receiving methotrexate or
leucovorin.

Measuring range: 0.6-20 ng/ml

Patient Preparation

Patient must be fasting

Reasons for Rejection

hemolysis.

Adult Reference Ranges

4.6-18.7
ng/mL